MST1 Is a Multifunctional Caspase-Independent Inhibitor of Androgenic Signaling
نویسندگان
چکیده
منابع مشابه
MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.
The MST1 serine-threonine kinase, a component of the RASSF1-LATS tumor suppressor network, is involved in cell proliferation and apoptosis and has been implicated in cancer. However, the physiologic role of MST1 in prostate cancer (PCa) is not well understood. Here, we investigated the possibility of a biochemical and functional link between androgen receptor (AR) and MST1 signaling. We showed ...
متن کاملTumor and Stem Cell Biology MST1 Is a Multifunctional Caspase-Independent Inhibitor of Androgenic Signaling
The MST1 serine–threonine kinase, a component of the RASSF1-LATS tumor suppressor network, is involved in cell proliferation and apoptosis and has been implicated in cancer. However, the physiologic role of MST1 in prostate cancer (PCa) is not well understood. Here, we investigated the possibility of a biochemical and functional link between androgen receptor (AR) and MST1 signaling. We showed ...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2011
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-10-4532